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248 In CML, mitochondrial and nuclear forms of STAT3 mediate TKI resistance through metabolic rewiring
Glutathione, the sole active ingredient, is a tripeptide composed of glutamine, cysteine, and glycine, and is recognized for its critical role in cellular defense against oxidative stress, as well as its involvement in numerous metabolic and detoxification pathways
They are also essential for maintaining healthy mitochondria as damaged or malfunctioning mitochondria are part of the cancer process
Previous literature has demonstrated that GSH levels are elevated in various tumors, including breast, colon, laryngeal, gastric, and lung cancers [16]
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