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Keywords: Glutathione, topical, antioxidant, pigmentary disorders, skin bleaching Introduction Glutathione, a low molecular weight thiol-tripeptide, is renowned for its potent antioxidant properties and has recently garnered attention for its potential skin-lightening effects, raising significant ethical debates regarding its use
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Chronic exposure has been associated with: Liver stress Immune suppression Increased inflammatory burden (14) Trichothecenes Often associated with Stachybotrys chartarum , trichothecenes can: Inhibit protein synthesis Disrupt mucosal immunity Intensify inflammatory signaling (15) Gliotoxin Produced by certain Aspergillus species, gliotoxin has immunosuppressive effects and may impair macrophage function and immune clearance (16)
After multivariate adjustment, a recently published study in female US nurses showed a non-statistically significant increased risk of psoriasis to the subgroup having low dietary folate equivalent (DFE) intake among those drinking over 5 nonlight beers per week as compared to the high DFE group in this study
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