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For the Sprague Dawley study, rats were single housed and had ad libitum access to a chow diet, kaolin pellets (K50001, Research Diets) and tap water
Also, the efficacy and safety of tirzepatide may have a wider perspective for its use beyond patients with T2DM or obesity [9, 10]
GLP-1 agonists activate receptors in the brain's appetite centres, reducing hunger and increasing satiety, whilst also slowing gastric emptying to prolong fullness after meals, collectively leading to reduced food intake and weight loss
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