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It is structurally modified from native human IGF-1 through two primary alterations: an arginine substitution at position 3 and the addition of a 13amino acid extension at the N-terminus
Presented for research literature review only Izumi Y et al
The IRB approval number is 2021KYLL032
[2] Diuretic medications such as loop diuretics (e.g., furosemide) or thiazides (e.g., chlorthalidone) can cause or worsen urinary frequency and nighttime awakenings to urinate
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