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5.1 Iron chelators and iron modifiers Iron chelators and modifiers effectively inhibit cellular ferroptosis by regulating the expression and activity of iron transporters and storage proteins, including transferrin and its receptor (TfR1), ceruloplasmin, ferroportin, divalent metal transporter 1 (DMT1), and other membrane iron transport proteins ( 2+ exists in the form of a labile iron pool and binds to low molecular weight compounds such as GSH ( To reduce intracellular Fe 3+ levels and prevent its conversion to Fe 2+ , iron chelators are widely employed

It improves overall circulation to injured areas, promotes cell migration from distant locations, and reduces systemic inflammation that can perpetuate the injury cycle

J Lipid Res 50(Suppl):S138

Glutatyon, solunum yoluyla alndnda akcier fonksiyonlarn desteklemek iin kullanlabilir