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Phase I reactions (primarily oxidation, reduction, and hydrolysis) structurally modify the parent compound but frequently generate reactive intermediates that can be more cytotoxic than the original molecules
As the science progressed, it was incorporated into dietary supplements and later into functional foods and beverages
Document baseline weight and body composition if possible
Moreover, N-glycosylation of SREBP cleavage-activating protein (SCAP) is essential for Golgi localization and activation of SREBP once EGFR induced glucose uptake in glioblastoma multiforme (GBM) (Cheng et al., 2015, 2016)
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