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In a study of 10 healthy male volunteers, omeprazole, in doses of 20 mg-40 mg per day, caused a significant decrease in the oral absorption of methylcobalamin, vitamin B12
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This means that it is the presence of this enzyme that causes weight gain
Risk factors for vitamin B12 deficiency include a decreased ability to absorb this vitamin due to low hydrochloric acid secretion, certain medications, or gastrointestinal disease and surgeries
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