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These domains are involved in homophilic (JAM-JAM) and heterophilic (JAM-other proteins) interactions
That enrolment breakdown is worth stating carefully, because the trials own abstract phrases it in a way that is easy to misread: it says 706 participants were assigned to cagrilintide 0.34.5 mg (100102 per dose group), 99 to liraglutide 3.0 mg, and 101 to placebo. Read literally, that would put the trial at over 900 people
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