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Subcutaneous injections are shallower, use thinner needles, and generally cause less discomfort
Based on the STEP-1 clinical trial, the average weight loss with semaglutide 2.4 mg weekly is 14.9% of body weight over 68 weeks (about 16 months)
doi:10.5326/JAAHA-MS-7232
The MHRA-approved SmPC reports that abdominal pain occurred in approximately 7-10% of participants receiving the 0.5 mg dose and 5-11% of those on the 1 mg dose
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