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Anti-Inflammatory Action: GHK-Cu exhibits potent anti-inflammatory properties by modulating cytokine expression, suppressing the activity of pro-inflammatory signals like NF-B and TNF-alpha

The increased risk of thrombosis and heart attack observed in some studies of COX-2 inhibitors may result from this mechanism (Conaghan 2012)

[23] Regulation [edit] Aside from deactivating radicals and reactive oxidants, glutathione participates in thiol protection and redox regulation of cellular thiol proteins under oxidative stress by protein S -glutathionylation, a redox-regulated post-translational thiol modification

PMID 2880477