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Results From the Combined Stack No controlled human trial has published weight-loss, body-composition, safety, or metabolic results for a retatrutide and MOTS-c combination
In Phase 2 research reported in The New England Journal of Medicine , participants began treatment with a low introductory dose, typically between 2 and 4 mg per week, and gradually increased to target doses ranging from 8 to 12 mg over several weeks
They're less effective than GLP-1s on average, but they're real options for patients on tight budgets
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