ERS represents one of the pathways through which chronic stress induces apoptosis in immune cells, and its pro-apoptotic effect has been observed to counteract the anti-apoptotic effect of STAT3, establishing cross-talk between the two (236)
*Correspondence: Giulio Bonomo, [email protected] These authors have contributed equally to this work ORCID: Giulio Bonomo, orcid.org/0000-0002-4749-7929 This article was submitted to Neuro-Oncology and Neurosurgical Oncology, a section of the journal Frontiers in Oncology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
The authors identified that the dorsal raphe nucleus (DR) has serotonergic neurons that secrete serotonin to hypothalamic nuclei and that GLP-1R activation promotes the activity of DR serotonin neurons
Nauck M, Weinstock RS, Umpierrez GE, Guerci B, Skrivanek Z, Milicevic Z