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Inflammation begets more inflammation
10.1007/s00125-023-06060-w 43 GaoY.YangG.ZhouY
Unfortunately, despite the remarkable progress in preclinical studies, research on these targets and signaling pathways has mainly remained in the animal and cellular experiments stage and has not yet entered the clinical trials stage
in most patients it reduces quality of life (QoL), requires long term daily treatment and is costly to the individuals, their families and to society
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