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NNMT catalyzes transfer of a methyl group from S-adenosyl-L-methionine (SAM) to nicotinamide, producing 1-methylnicotinamide (1-MNA) and S-adenosyl-L-homocysteine
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Although more research is needed to solidify these findings, evidence published by the American Academy of Pain Medicine points to the efficacy of B12 as an adjunctive treatment alongside lidocaine for pain management
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