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Post hoc analyses examined whether intervention effects on plasma TMAO differed by age and sex

Zhou et al., 2022) reveals markedly altered abundance and diversity of gut microbiota in patients with diabetes compared to healthy individuals, characterized by low-diversity dysbiosis and an overgrowth of opportunistic pathogens

However, they stressed that the findings show only positive links not established evidence of safety or therapeutic benefit during or before pregnancy

Unbound iron enters the cardiomyocytes through the L-type calcium channels ( The fact that cardiomyocyte iron overload is a storage problem and not an infiltrative process indicates that iron can be removed to reverse cardiac iron overload and associated damage ( Molecular mechanism of myocardial injury caused by cardiac iron overload in thalassemia Iron overload is a common feature in patients with -thalassemia, but the molecular mechanism of cardiac damage caused by iron overload in thalassemia is poorly understood