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AGEs react with amino acid residues in proteins, forming irreversible modifications that negatively affect sperm, including reduced sperm count, decreased motility, increased morphological abnormalities, residual histones, fish sperm protein deficiency, sperm DNA fragmentation, decreased antioxidant capacity in the testes, and elevated levels of receptor for advanced glycation end products (RAGE) and carboxymethyl lysine (CML) proteins [160]
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Also, depending on these kinds of treatments raises moral and mental issues about social beauty standards and the chance of having problems with body image
Acknowledgements The work was supported by the National Research Foundation Singapore under its Competitive Research Programme (grant no
