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The diagram in d was created using BioRender
Figure 3 Another analog, PF-05231023, is a 190 kDa molecule consisting of human FGF21 covalently linked to each Fab region of a humanized IgG1 mAb scaffold, resulting in a 2:1 stoichiometry of FGF21 molecules per scaffold (292)
Reducing the amount of glucose in the bloodstream improves insulin sensitivity and promotes better control of blood sugar levels
Also, these effects often resolve within 24 hours
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