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In clinical trials, 100% of healthy volunteers experienced this chromaturia with administration of 5g hydroxocobalamin with other common effects including erythema, rash (predominantly acneiform appearance) and increased blood pressure
Semaglutide is generally well-tolerated, but as with any medication, there may be side effects
Standardization of testing samples and methods is still lacking, and marked individual and metabolic variations exist (Kaltsas et al., 2024)
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