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Histidine (His) is a major N-donor ligand important for metal chelation in (metal hyperaccumulator) plants
Originally isolated from human plasma in the 1970s, GHK-Cu is chemically distinct because it acts as a feedback signal for tissue remodeling
For laboratory work such a compact and recognisable format can be convenient when managing reference material, certainly in a setup where several peptides are studied alongside each other and mix-ups must be prevented
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