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A recent prospective case-control study (17) showed that in a 10-year period, regardless of the level of baseline TMAO, the final increase in TMAO was significantly associated with an increased risk of CHD, and the TMAOCHD relationship could be improved by dietary changes (17)
2011;300(3):F6419
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Notably, research involving astrocytes cultured from a transgenic AD mouse model overexpressing apoE demonstrated that melatonin reversed the A aggregation-promoting activity of this protein [74]
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