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Iversen L, Gibbons S, Treble R, Setola V, Huang XP, Roth BL (2013) Neurochemical profiles of some novel psychoactive substances

GLP-1RAs can cross the bloodbrain barrier and activate brain GLP-1 receptors, leading to neuroprotection by improving insulin signaling, reducing tau hyperphosphorylation, and enhancing cognitive function in diabetic and aging models

While you cannot spot-reduce fat from specific areas, the substantial weight loss associated with Retatrutide typically includes reduction in abdominal fat

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