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Specifically, vitamins B6 is essential for the synthesis of DNA and RNA, which is necessary for the growth and proliferation of immune cells

Options include: Changing from one oral tablet formulation to another with different excipients Discussing sublingual preparations as an alternative (though evidence doesn't suggest superior absorption to oral tablets) For those on injections, checking the specific product's SmPC for excipient information In the UK, hydroxocobalamin injection is the licensed first-line treatment for B12 deficiency requiring parenteral therapy

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Current limitations include the heterogeneity of ASD, the challenges in detecting GABAergic abnormalities (e.g., reliance on invasive or low-resolution methods like MRI spectroscopy), and the need for more targeted drug development to minimize off-target effects