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By: Cami Eastman, RDN, LD on 02/26/2026 As more people in midlife turn to GLP-1 medications for metabolic support, questions are emerging about how these drugs interact with hormone replacement therapy (HRT), what the long-term effects may be for postmenopausal bodies, and what nutritional strategies are most important to protect health
10.1016/j.arr.2019.100942 77 FarB
Tirzepatide activates both GLP-1 and GIP receptors, engaging a dual mechanism that may produce more potent weight loss and metabolic effects in some patients
Ethics declarations Ethics Approval and Consent to Participate Written informed consent was obtained from all individual participants included in the study
