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Eur J Pharm Biopharm 163:6071 Teraoka M, Hato N, Inufusa H, You F (2024) Role of oxidative stress in sensorineural hearing loss
However, certain patient populations might theoretically benefit from the anti-inflammatory properties of these agents when used for approved indications
Indeed, in the cardiovascular outcome trial (CVOT) for semaglutide, SUSTAIN 6 a relatively short (two-year) and small (3,297 individuals) preregistration trial (an extensive CVOT in obese individuals without T2DM (SELECT) is expected to complete in 2024) HbA 1c was powerfully and durably reduced
Additionally, both drug classes exert favourable effects on body weightGLP-1 receptor agonists through appetite suppression and delayed gastric emptying, SGLT2 inhibitors through caloric loss via glycosuria
