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Using 1 L from each digested sample, high-performance liquid chromatography (HPLC) was performed using the UltiMate 3000 apparatus (Thermo Fisher, San Jose, CA)
Week A Day 1: 500mg NAD IV ( 2-3.5 hrs) Day 4: 100mg NAD SQ Day 6: 100mg NAD SQ Daily: 500mg NR/NMN in the morning Week B Daily: 500mg NR/NMN in the morning Day 1: 100mg NAD SQ Day 4: 100mg NAD SQ Day 6: 100mg NAD SQ Use this cycle and keep repeating, modifying it as you see fit
Effectiveness depends on age, baseline hormone levels, pituitary responsiveness, and treatment goals
longer-duration trials are ongoing For a 250 lb individual: approximately 72 lbs (32 kg) lost at 68 weeks Comparison of Weight Loss Trajectories The following table compares the weight loss trajectories of retatrutide, tirzepatide, and semaglutide at their highest studied doses
