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2,5,8 Ulcers on the bladder wall, called Hunner lesions (Figure 1), are present in about 510% of cases of IC/BPS, although it is possible that they are under-diagnosed and are present in up to half of all IC/BPS cases
In particular, the mitochondrial inner membrane is impermeable to fatty acyl-CoA thioesters and, thus, the specialized CS, for transporting fatty acids across mitochondrial membranes has evolved 18
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