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Karavia, Andreas Pittaras, Ourania Andreopoulou, Aikaterini Hatziri, Amalia Makrydimitri, Dimitrios Anagnostopoulos, Patroklos Vareltzis, Kyriakos E
02 Review Candidacy Relevant health history, allergies, medications, and pregnancy or breastfeeding status may be reviewed before treatment
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This Fc domain serves a dual function: it sterically hinders access to DPP-4, thereby protecting the GLP-1 moiety from enzymatic degradation, and it engages the neonatal Fc receptor (FcRn), facilitating receptor-mediated recycling and preventing lysosomal degradation following cellular uptake
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