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Controlled Release: Provides a sustained release mechanism, ensuring prolonged antioxidant protection and tyrosine inhibition
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In line with our observation of HMOX1 and Hsp70 upregulation, the transcription factor NRF2 (Nuclear Factor Erythroid-Derived 2-Related Factor 2), which controls expression of HMOX1 and other stress-responsive targets 54 , was increased after CCW16 and PROTAC treatment ( Figure 2E )
Pernicious anaemia , an autoimmune condition affecting approximately 2% of the UK population over 60 (and about 0.10.2% overall), destroys gastric parietal cells, eliminating intrinsic factor production and severely impairing B12 absorption
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