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That extended duration is what makes weekly dosing possible, but it also means the body is exposed to sustained amylin receptor activation far beyond what natural physiology produces
The genuine unknown is long-term effects in humans
maintenance phase is the heavy draw 26 weeks 13 vials Standard Phase 2 duration 32 weeks 16 vials Phase 2 T2D study duration 68 weeks 30 vials REDEFINE 1 / REDEFINE 2 endpoint duration Peptide Vials (10 mg vial, 2.4 mg/week target) Each 10 mg vial covers about 4 weekly doses at 2.4 mg/week
However, the additional ingredients may affect the appearance of the reconstituted solution (B12 adds a pink tint, for example) and may have their own stability profiles
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