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Several neuroprotective drugs have been shown to reduce accumulation of aggregated, ubiquitinated proteins
These medications may be appropriate for acute pain, neuropathic pain, or specific conditions as per NICE guidance, but require individual assessment, careful monitoring, and time-limited use
However, the recent FDA approvals of Wegovy (2021) and Zebound (2023) for weight loss have been met with a tremendous increase in demand for these drugs
It can occur due to the drugs effect on gastrointestinal motility, potentially leading to esophagitis or erosions
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