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GLP-1 receptor agonists (semaglutide, liraglutide, dulaglutide) and the GIP/GLP-1 dual agonist tirzepatide were studied in STEP (semaglutide, weight management, NEJM 2021), SURMOUNT (tirzepatide, weight management, NEJM 2022), and SURMOUNT-OSA (tirzepatide, obstructive sleep apnea, NEJM 2024)
Kumar says that retatrutide will likely be best suited for "people who we consider non-responders to existing cardiometabolic medications," such as Wegovy and Ozempic
These include: Severe pain or discomfort that does not improve with home remedies
Like cysteine, glutathione contains the crucial thiol (-SH) group that makes it an effective antioxidant
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