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Individual tolerability varies
Mild-to-moderate diarrhea affects roughly 20% of GLP-1 users, while severe casesdefined as multiple loose stools daily that interfere with activitiesoccur in fewer than 5%
Monocytes from patients with rheumatoid arthritis and type 2 diabetes mellitus display an increased production of interleukin (IL)-1 via the nucleotide-binding domain and leucine-rich repeat containing family pyrin 3(NLRP3)-inflammasome activation: a possible implication for therapeutic decision in these patients
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