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These changes result in reduced intratesticular testosterone concentrations, testicular atrophy, and impaired spermatogenesis (77)
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In the event DSIP does ultimately undergo clinical development, intranasal administration can ensure a higher degree of patient compliance by eliminating side effects and discomfort commonly associated with peptide injections
Following endocytosis, Fe is reduced to Fe by the six-transmembrane epithelial antigen of the prostate 3 (STEAP3), and subsequently stored in mitochondria, the endoplasmic reticulum, ferritin, and the iron pool
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