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insulin glargine The SURPASS-AP-Combo trial enrolled 917 adults with type 2 diabetes (age 18 years, inadequately controlled by previous metformin therapy and insulin-naive), who received tirzepatide 5 mg (n = 230), 10 mg (n = 228), 15 mg (n = 229), or insulin glargine (n = 230)
A review of 225 published cases
Type 2 diabetes and obesity dramatically increase the risk of dementia by up to 60%, accelerating amyloid pathology, cerebrovascular damage, and insulin resistance in the brain, sometimes described as type 3 diabetes [1]
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