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Quick Answer: GLP-1 medications may not work as expected due to inadequate dosage, incorrect administration technique, insufficient treatment duration, lifestyle factors, concurrent medications, advanced beta-cell dysfunction, or unrealistic expectations about timeframes and outcomes

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Less common side effects acid or sour stomach belching excess air or gas in stomach feeling pressure in the stomach heartburn passing gas stomach discomfort, swelling, tenderness, or upset For healthcare professionals Applies to semaglutide: oral tablet, subcutaneous solution

However, human safety profiles are unknown , as these compounds have not undergone comprehensive clinical evaluation