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PloS one 16 (5), e0250486

Although there have been no specific trials to show cardiorenal benefit for GLP-1RA or SGLT2i when used as first-line therapy or as monotherapy or in newly diagnosed T2D, the benefit seen in the CV outcome trials has not been found to vary with the duration of diabetes, suggesting that similar benefits might be seen early in the course of disease.4 The benefits are also not dependent on the presence of metformin

B12 for Weight Loss: How It Supports Fat Burning While B12 injections are not a magic solution on their own, they support weight management by optimizing the systems your body relies on to burn calories efficiently

This mirrors the timelines seen with approved hair therapies, which are themselves evaluated over 6-12 months