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4b,c) and the inhibitor BSO (Fig

The assay was designed to demonstrate the biochemical activity of c-met binding sites including Y198 and Y250 (in K1 and K2 domains of HGF, respectively) by significant changes in optical absorbance (expressed as relative unit) within a range from a baseline level (a negative control without HGF

Lipolysis without GH-receptor activity Metabolic studies of the synthetic lipolytic domain showed AOD-9604 stimulating fat breakdown in fat-cell and animal models without binding the growth-hormone receptor or raising IGF-1 [1]

Ammonium formate (1 mol/L) and LC/MS-grade formic acid were purchased from Fujifilm Wako Chemical Industries (Osaka, Japan)