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The SELECT trial demonstrated cardiovascular benefits of semaglutide independent of weight loss, leading to a cardiovascular risk reduction indication that does not require a specific BMI
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Go on While both T2D and obese or overweight patients prescribed semaglutide demonstrated a substantially higher risk for NAION vs those prescribed other medications, the authors noted that this risk does not seem to be due to difference in baseline characteristics between the cohorts. Important finding: Survival analyses from both groups determined that NAION may have the greatest risk of developing within the first year of starting semaglutide prescription use
