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It directly inhibited the stearoyl-CoA desaturase-1 (SCD1) protein to trigger ferroptosis of ovarian cancer, evidenced by the increased ROS, total iron, and Fe 2+ levels and downregulation of ferroptosis inhibitors (SLC7A11 and GPX4), thus suppressing cancer progression in the SKOV-3 xenograft model (Liu et al., 2022)

DAPI-stained nuclei with blue fluorescence were viewed under laser confocal microscope (LSM 510

We considered the possibility that the downregulated expression of exons II and III in ob/ob mice was caused by obesity, which cannot be normalized by acute leptin treatment

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