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In the original characterization work, metabolomic profiling of treated cells and animals indicated that MOTS-c is associated with interference in the folate cycle, which in turn appears to slow de novo purine biosynthesis
Novo JP, Martins B, Raposo RdaS, Pereira FC, Ori RB, Malva JO, Ribeiro C (2021a) Cellular and molecular mechanisms mediating methylmercury neurotoxicity and neuroinflammation
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