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Other natural compounds with evidence for stimulating GLP-1 include curcumin from turmeric, which activates similar metabolic pathways, green tea catechins that influence incretin hormone production, and specific amino acid combinations that trigger L-cell signaling
Published 2017 Feb 15
The preclinical data suggests the hypothesis that inhibitory GIPR + neurons act specifically on GLP-1R + neurons that drive nausea and food aversion or avoidance to dampen GLP-1R mediated nausea without reducing efficacy, potentially lifting the ceiling of GLP-1R agonist-induced reductions in body weight
The FDAapproved tesamorelin dose is 2 mg SC daily [3] , while ipamorelin is commonly studied at 100300 mcg SC daily [4]
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