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5a), approved for the treatment of amyotrophic lateral sclerosis, increases ROS levels by multiple mechanisms, including decreasing LDH-A and NAD + levels to increase oxidative stress, as well as interfering with the xCT antiporter to block the cystineglutamate pump
One of very few compounds with documented telomerase activation in vitro and animal studies
Journal of Orthopaedic Research, 29(1), 144-150
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