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Stock # 014647, Jackson Laboratories) promoter generated mouse lines with endogenous Gcg reactivated specifically in intestinal epithelial L cells ( Gcg RA VilCre ) and pancreatic alpha cells and within the duodenum ( Gcg RA PDX1Cre ), respectively [9]
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Several passed centralized procurementkey for commercial scale-up
It targets one hormone pathway, acting on the same receptors as naturally produced glucagon-like peptide-1 to regulate appetite, slow gastric emptying, and support insulin release
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