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Subjects from the PIONNEER 7 study showed comparable satisfaction between oral semaglutide and sitagliptin [41], a dipeptidyl peptidase-4 inhibitor (DPP-4i) largely used in monotherapy or combination when first-line treatment does not achieve adequate glycaemic control, but sitagliptin does not provide any cardiovascular benefit [95]
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Allergic Reactions (Rare): Although rare, some individuals can have an allergic reaction to the injection, ranging from a rash or itching to more severe symptoms like swelling of the face, tongue, or throat, dizziness, or difficulty breathing
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