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In addition, the information pharmacists mined and analyzed the ADEs data of GLP-1RA in the FAERS database through ROR and PRR [34, 35], with a view to discovering new potential risk signals and providing effective references for the safe clinical use of the GLP-1RA class of drugs
Semaglutide interacted with circumventricular organs, where GLP-1R expression is abundant, and with regions protected by the BBB (lateral septal nucleus, nucleus tractus solitarius, hypothalamic arcuate nucleus) (102)
Evangelista, M., Koverech, A., Messano, M., and Pescosolido, N
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