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Researchers hypothesized that, while the increased thyroid hormone increased carnitine synthesis, it also accelerated mitochondrial fatty acid oxidation (similar to what was seen to happen in a hyperthyroid state), which reduced carnitine levels
No additional updates are warranted to product information for any GLP-1 drug, the agency saidboth Wegovy and Ozempic already indicate on their safety labels the drugs have caused thyroid tumors in studies with rodents, but note it is unknown whether the drugs can cause thyroid tumors or thyroid cancer
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