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Rybelsus has now demonstrated proven cardiovascular risk reduction in the landmark SOUL trial (McGuire et al., NEJM 2025)
Here's another word picture to help explain this process: This process of methylation is like a factory line where ' methyl groups ' are being created
It works through two mechanisms: inhibiting the enzyme tyrosinase (which is essential for melanin synthesis) and shifting the melanin production pathway from eumelanin (darker pigment) to pheomelanin (lighter pigment)
Because Wegovy is an MHRA approved weight loss injection and relatively new to the market, it is under close safety monitoring
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