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In the STEP 1 clinical trial published in the New England Journal of Medicine, patients using semaglutide 2.4 mg once weekly lost an average of 14.9% of their body weight over 68 weeks, with over 50% of participants achieving at least 15% weight loss

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Related reading: More Than a Number: Bariatric Surgery, GLP-1 Medications and Tools to Treat Obesity

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Most people lose about five to ten percent of their body weight on phentermine which is helpful, but not groundbreaking

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