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These findings further suggest that an additional round of negative selection against IL-1 reduced the stability of these proteases, making them ineffective at initiating cell death

Tumor tissues undergo lipid remodeling by aberrantly augmenting multiple pathways, including de novo lipid synthesis, exogenous uptake, lipid droplet (LD) storage, and lipid oxidation, thereby ensuring the structural diversity of lipid pools and their long-term maintenance in an environmentally dependent manner [16]