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People with Digestive Issues: Conditions like Crohns disease, celiac disease, or irritable bowel syndrome can interfere with B12 absorption, making injections a more effective method of getting the nutrient
The metabolism and elimination of NAD+ (and its by-products) could be altered in advanced hepatic or renal dysfunction, and high-dose NAD+ might theoretically affect cardiovascular dynamics, so practitioners generally avoid or closely supervise NAD+ use in such settings
Drinking plenty of water is key
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